reasoning benchmark
MedChemBench (Internal)
MedChemBench is an internal OpenAI evaluation of medicinal-chemistry reasoning, testing whether models can support drug-discovery-relevant chemistry analysis and decision-making.
Updated Aug 11, 2026
Models3
Model coverage3
MetricScore
EvidenceB
MedChemBench (Internal) Ranking
Higher score ranks better on this benchmark.
| 1 | OP | 48.3% | 100.0% | 3 | C | |
| 2 | OP | 35.0% | 50.0% | 3 | C | |
| 3 | OP | 30.4% | 0.0% | 3 | C |
MedChemBench (Internal) Score Distribution
A closer view of the leading scores on this benchmark.
MedChemBench (Internal) Highlights
The leading models and scores on this benchmark.
What is MedChemBench (Internal)?
What MedChemBench (Internal) measures and how its scores work.
MedChemBench is an internal OpenAI evaluation of medicinal-chemistry reasoning, testing whether models can support drug-discovery-relevant chemistry analysis and decision-making.
Scores are shown in ratio. This benchmark is not independently verified and has an evidence level of B.
- Family
- MedChemBench (Internal)
- Modality
- text
- Primary category
- reasoning
- Score direction
- higher
- LLMBoard eligible
- Yes
- Evaluation key
- medchembench|llm-stats-current
Benchmark scores retain their original unit. Overall score eligibility is shown separately.
FAQ
Common questions about MedChemBench (Internal).
Which model scores highest on MedChemBench (Internal)?
GPT-5.6 Sol is currently ranked first with 48.3%.
What does MedChemBench (Internal) measure?
MedChemBench is an internal OpenAI evaluation of medicinal-chemistry reasoning, testing whether models can support drug-discovery-relevant chemistry analysis and decision-making.
Is a higher score better?
Yes. Higher values rank better for this benchmark.
How many models are compared?
3 model results are currently shown.
Does this benchmark affect the overall score?
Yes. This benchmark can contribute to the current LLMBoard capability score.